Aspects of this topic are discussed in the following places at Britannica.
...predilection, whereas others occur in all pure and mixed breeds. Large- and giant-breed dogs, such as Irish setters, St. Bernards, bloodhounds, and Great Danes, are prone to a condition known as gastric dilatation volvulus (GDV). This disease causes the stomach to twist in the abdominal cavity, cutting off the blood supply and filling the stomach with gas. GDV is always a medical emergency...
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